The in vitro anti-inflammatory effects of recombinant anti-CD25 immunotoxin on lamina propria T cells of patients with inflammatory bowel disease are not sufficient to cure experimental colitis in mice.
第一作者:
K,Pfister
第一单位:
Department of Internal Medicine II, Saarland University, Homburg/Saar, Germany.
作者:
主题词
成年人(Adult);动物(Animals);抗体, 单克隆(Antibodies, Monoclonal);细胞凋亡(Apoptosis);结肠炎(Colitis);女(雌)性(Female);人类(Humans);免疫毒素类(Immunotoxins);炎症(Inflammation);炎性肠疾病(Inflammatory Bowel Diseases);干扰素γ(Interferon-gamma);肠黏膜(Intestinal Mucosa);男(雄)性(Male);小鼠(Mice);小鼠, 近交BALB C(Mice, Inbred BALB C);中年人(Middle Aged);受体, 白细胞介素2(Receptors, Interleukin-2);单链抗体(Single-Chain Antibodies);T淋巴细胞(T-Lymphocytes);三硝基苯磺酸(Trinitrobenzenesulfonic Acid)
DOI
10.1007/s003840100336
PMID
12014425
发布时间
2019-10-25
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