Mutations of the BRAF gene in human cancer.-论文-万方医学网

作者： Helen,Davies ^[1] ; Graham R,Bignell ; Charles,Cox ; Philip,Stephens ; Sarah,Edkins ; Sheila,Clegg ; Jon,Teague ; Hayley,Woffendin ; Mathew J,Garnett ; William,Bottomley ; Neil,Davis ; Ed,Dicks ; Rebecca,Ewing ; Yvonne,Floyd ; Kristian,Gray ; Sarah,Hall ; Rachel,Hawes ; Jaime,Hughes ; Vivian,Kosmidou ; Andrew,Menzies ; Catherine,Mould ; Adrian,Parker ; Claire,Stevens ; Stephen,Watt ; Steven,Hooper ; Rebecca,Wilson ; Hiran,Jayatilake ; Barry A,Gusterson ; Colin,Cooper ; Janet,Shipley ; Darren,Hargrave ; Katherine,Pritchard-Jones ; Norman,Maitland ; Georgia,Chenevix-Trench ; Gregory J,Riggins ; Darell D,Bigner ; Giuseppe,Palmieri ; Antonio,Cossu ; Adrienne,Flanagan ; Andrew,Nicholson ; Judy W C,Ho ; Suet Y,Leung ; Siu T,Yuen ; Barbara L,Weber ; Hilliard F,Seigler ; Timothy L,Darrow ; Hugh,Paterson ; Richard,Marais ; Christopher J,Marshall ; Richard,Wooster ; Michael R,Stratton ; P Andrew,Futreal

作者单位： Cancer Genome Project, The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, CB10 1SA, UK. ^[1]

主题词 3T3细胞(3T3 Cells);氨基酸序列(Amino Acid Sequence);动物(Animals);碱基序列(Base Sequence);细胞分裂(Cell Division);细胞转化, 肿瘤(Cell Transformation, Neoplastic);DNA突变分析(DNA Mutational Analysis);酶激活(Enzyme Activation);人类(Humans);MAP激酶信号系统(MAP Kinase Signaling System);黑色素瘤(Melanoma);小鼠(Mice);丝裂原激活蛋白激酶类(Mitogen-Activated Protein Kinases);分子序列数据(Molecular Sequence Data);突变, 误义(Mutation, Missense);肿瘤(Neoplasms);蛋白质结构, 三级(Protein Structure, Tertiary);原癌基因蛋白质B-raf(Proto-Oncogene Proteins B-raf);原癌基因蛋白质c-raf(Proto-Oncogene Proteins c-raf);肿瘤细胞, 培养的(Tumor Cells, Cultured);ras蛋白质类(ras Proteins)

DOI 10.1038/nature00766

PMID 12068308

发布时间 2022-04-13

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Mutations of the BRAF gene in human cancer.

Nature

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Mutations of the BRAF gene in human cancer.

Nature

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Nature

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