Mutations C677T and A1298C of the 5,10-methylenetetrahydrofolate reductase gene and fasting plasma homocysteine levels are not associated with the increased risk of venous thromboembolic disease.
第一作者:
T B,Domagala
第一单位:
Department of Medicine, Jagellonian University School of Medicine, Krakow, Poland.
作者:
医学主题词
3'非翻译区(3' Untranslated Regions);活化蛋白C抵抗(Activated Protein C Resistance);青少年(Adolescent);成年人(Adult);老年人(Aged);老年人, 80以上(Aged, 80 and over);等位基因(Alleles);氨基酸取代(Amino Acid Substitution);密码子(Codon);因子Ⅴ(Factor V);禁食(Fasting);女(雌)性(Female);基因频率(Gene Frequency);疾病遗传易感性(Genetic Predisposition to Disease);基因型(Genotype);高半胱氨酸(Homocysteine);人类(Humans);高同种半胱氨酸血症(Hyperhomocysteinemia);男(雄)性(Male);亚甲基四氢叶酸还原酶(NADPH)(Methylenetetrahydrofolate Reductase (NADPH2));中年人(Middle Aged);突变, 误义(Mutation, Missense);作用于CH-NH族供体的氧化还原酶类(Oxidoreductases Acting on CH-NH Group Donors);点突变(Point Mutation);波兰(Poland);凝血酶原(Prothrombin);危险因素(Risk Factors);血栓形成倾向(Thrombophilia);静脉血栓形成(Venous Thrombosis)
DOI
10.1097/00001721-200207000-00007
PMID
12138370
发布时间
2019-09-16
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