换一批
换一批Development of a real-time in vivo transcription assay: application reveals pregnane X receptor-mediated induction of CYP3A4 by cancer chemotherapeutic agents.
第一作者：
Erin,Schuetz
第一单位：
Department of Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, Tennessee 38105, USA. erin.schuetz@stjude.org
作者：
主题词
动物(Animals);抗肿瘤药(Antineoplastic Agents);细胞色素P-450 CYP3A(Cytochrome P-450 CYP3A);细胞色素P450酶系统(Cytochrome P-450 Enzyme System);酶诱导(Enzyme Induction);依托泊甙(Etoposide);基因, 报告(Genes, Reporter);人类(Humans);男(雄)性(Male);小鼠(Mice);小鼠, 近交C57BL(Mice, Inbred C57BL);混合功能氧化酶类(Mixed Function Oxygenases);RNA, 信使(RNA, Messenger);大鼠(Rats);受体, 胞质和核(Receptors, Cytoplasmic and Nuclear);受体, 类固醇(Receptors, Steroid);他莫昔芬(Tamoxifen);托泊替坎(Topotecan);转录, 遗传(Transcription, Genetic)
DOI
10.1124/mol.62.3.439
PMID
12181418
发布时间
2025-02-13
- 浏览12
Molecular pharmacology
439-45页
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