Vav1 and Ly-GDI two regulators of Rho GTPases, function cooperatively as signal transducers in T cell antigen receptor-induced pathways.
作者:
主题词
抗原, 分化, T淋巴细胞(Antigens, Differentiation, T-Lymphocyte);钙(Calcium);细胞周期蛋白质类(Cell Cycle Proteins);细胞膜(Cell Membrane);细胞骨架(Cytoskeleton);DNA结合蛋白质类(DNA-Binding Proteins);基因表达调控, 酶学(Gene Expression Regulation, Enzymologic);遗传载体(Genetic Vectors);鸟嘌呤核苷酸游离阻滞剂(Guanine Nucleotide Dissociation Inhibitors);人类(Humans);水解作用(Hydrolysis);免疫印迹法(Immunoblotting);Jurkat细胞(Jurkat Cells);淋巴细胞活化(Lymphocyte Activation);显微镜检查, 共焦(Microscopy, Confocal);显微镜检查, 荧光(Microscopy, Fluorescence);模型, 遗传学(Models, Genetic);NFATC转录因子类(NFATC Transcription Factors);核蛋白质类(Nuclear Proteins);磷酰化(Phosphorylation);沉淀素试验(Precipitin Tests);蛋白质类(Proteins);原癌基因蛋白质类(Proto-Oncogene Proteins);原癌基因蛋白质c-vav(Proto-Oncogene Proteins c-vav);重组融合蛋白质类(Recombinant Fusion Proteins);信号传导(Signal Transduction);亚细胞部分(Subcellular Fractions);温度(Temperature);时间因素(Time Factors);转录因子(Transcription Factors);肿瘤抑制蛋白质类(Tumor Suppressor Proteins);C型磷脂酶类(Type C Phospholipases);酪氨酸(Tyrosine);ρGTP结合蛋白质类(rho GTP-Binding Proteins);src同源域(src Homology Domains)
DOI
10.1074/jbc.M204299200
PMID
12386169
发布时间
2021-02-06
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