Mechanism of biochemical action of substituted 4-methylbenzopyran-2-ones. Part 9: comparison of acetoxy 4-methylcoumarins and other polyphenolic acetates reveal the specificity to acetoxy drug: protein transacetylase for pyran carbonyl group in proximity to the oxygen heteroatom.
第一作者:
Ishwar,Singh
第一单位:
Bioorganic Laboratory, Department of Chemistry, University of Delhi, India.
作者:
医学主题词
乙酸盐类(Acetates);乙酰基转移酶类(Acetyltransferases);动物(Animals);香豆素类(Coumarins);类黄酮物质(Flavonoids);男(雄)性(Male);微粒体, 肝(Microsomes, Liver);分子结构(Molecular Structure);NADH脱氢酶(NADH Dehydrogenase);酚类(Phenols);聚合物(Polymers);吡喃类(Pyrans);大鼠(Rats);大鼠, Wistar(Rats, Wistar);构效关系(Structure-Activity Relationship);底物特异性(Substrate Specificity)
DOI
10.1016/s0968-0896(02)00257-2
PMID
12413864
发布时间
2019-09-01
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