A site in the fourth membrane-associated domain of the N-methyl-D-aspartate receptor regulates desensitization and ion channel gating.
第一作者:
Hong,Ren
第一单位:
Unit on Cellular Neuropharmacology, Laboratory of Molecular and Cellular Neurobiology, National Institute on Alcohol Abuse and Alcoholism, Bethesda, Maryland 20892-8115, USA.
作者:
医学主题词
氨基酸序列(Amino Acid Sequence);细胞系(Cell Line);兴奋性氨基酸激动剂(Excitatory Amino Acid Agonists);甘氨酸(Glycine);人类(Humans);离子通道闸门(Ion Channel Gating);甲硫氨酸(Methionine);模型, 分子(Models, Molecular);分子序列数据(Molecular Sequence Data);诱变, 定点(Mutagenesis, Site-Directed);N-甲基天冬氨酸(N-Methylaspartate);膜片钳术(Patch-Clamp Techniques);蛋白质结构, 二级(Protein Structure, Secondary);蛋白质结构, 三级(Protein Structure, Tertiary);受体, N-甲基-D-天冬氨酸(Receptors, N-Methyl-D-Aspartate);回归分析(Regression Analysis);序列比对(Sequence Alignment)
DOI
10.1074/jbc.M209486200
PMID
12414797
发布时间
2021-02-06
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