Administration of interleukin-12 and -18 enhancing the antitumor immunity of genetically modified dendritic cells that had been pulsed with Semliki forest virus-mediated tumor complementary DNA.
第一作者:
Ryuya,Yamanaka
第一单位:
Clinical Gene Therapy Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland, USA. ryaman@pop11.odn.ne.jp
作者:
医学主题词
动物(Animals);抗体生成(Antibody Formation);CD4阳性T淋巴细胞(CD4-Positive T-Lymphocytes);CD8阳性T淋巴细胞(CD8-Positive T-Lymphocytes);DNA, 互补(DNA, Complementary);DNA, 肿瘤(DNA, Neoplasm);树突细胞(Dendritic Cells);遗传载体(Genetic Vectors);神经胶质瘤(Glioma);免疫疗法(Immunotherapy);干扰素γ(Interferon-gamma);白细胞介素12(Interleukin-12);白细胞介素18(Interleukin-18);杀伤细胞, 天然(Killer Cells, Natural);小鼠(Mice);西门利克森林病毒(Semliki forest virus);T淋巴细胞, 细胞毒性(T-Lymphocytes, Cytotoxic);肿瘤细胞, 培养的(Tumor Cells, Cultured)
DOI
10.3171/jns.2002.97.5.1184
PMID
12450042
发布时间
2012-11-15
- 浏览37
Journal of neurosurgery
1184-90页
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