Red wine polyphenolic compounds inhibit vascular endothelial growth factor expression in vascular smooth muscle cells by preventing the activation of the p38 mitogen-activated protein kinase pathway.
第一作者:
Min-Ho,Oak
第一单位:
Pharmacologie et Physico-Chimie des Interactions Cellulaires et Moléculaires, UMR CNRS 7034, Université Louis Pasteur de Strasbourg, Illkirch, France.
作者:
主题词
雄二烯类(Androstadienes);动物(Animals);抗氧化剂(Antioxidants);细胞, 培养的(Cells, Cultured);酶抑制剂(Enzyme Inhibitors);类黄酮物质(Flavonoids);人类(Humans);咪唑类(Imidazoles);MAP激酶信号系统(MAP Kinase Signaling System);丝裂原激活蛋白激酶类(Mitogen-Activated Protein Kinases);肌, 平滑, 血管(Muscle, Smooth, Vascular);鎓类化合物(Onium Compounds);酚类(Phenols);磷酰化(Phosphorylation);血小板源性生长因子(Platelet-Derived Growth Factor);蛋白质加工, 转译后(Protein Processing, Post-Translational);吡啶类(Pyridines);RNA, 信使(RNA, Messenger);大鼠(Rats);活性氧(Reactive Oxygen Species);凝血酶(Thrombin);转化生长因子β(Transforming Growth Factor beta);转化生长因子β1(Transforming Growth Factor beta1);血管内皮生长因子A(Vascular Endothelial Growth Factor A);葡萄酒(Wine);p38丝裂原活化蛋白激酶类(p38 Mitogen-Activated Protein Kinases)
DOI
10.1161/01.ATV.0000070101.70534.38
PMID
12676803
发布时间
2018-11-30
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