Functional characterization of human UDP-glucuronosyltransferase 1A9 variant, D256N, found in Japanese cancer patients.
作者:
主题词
氨基酸取代(Amino Acid Substitution);动物(Animals);抗肿瘤药(Antineoplastic Agents);天冬酰胺(Asparagine);天冬氨酸(Aspartic Acid);COS细胞(COS Cells);喜树碱(Camptothecin);外显子(Exons);遗传变异(Genetic Variation);葡糖醛酸盐类(Glucuronates);葡糖醛酸(Glucuronic Acid);葡糖醛酸基转移酶(Glucuronosyltransferase);人类(Humans);日本(Japan);突变(Mutation);肿瘤(Neoplasms);多态性, 单核苷酸(Polymorphism, Single Nucleotide);转染(Transfection)
DOI
10.1124/jpet.103.051250
PMID
12730278
发布时间
2021-12-03
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