Identification of a novel Krüppel-associated box domain protein, Krim-1, that interacts with c-Myc and inhibits its oncogenic activity.
第一作者:
Hanjo,Hennemann
第一单位:
Institut für Zellbiologie (Tumorforschung), Universitätsklinikum Essen, Virchowstrasse 173, D-45122 Essen, Germany.
作者:
医学主题词
3T3细胞(3T3 Cells);氨基酸序列(Amino Acid Sequence);动物(Animals);结合部位(Binding Sites);COS细胞(COS Cells);载体蛋白质类(Carrier Proteins);细胞核(Cell Nucleus);细胞转化, 肿瘤(Cell Transformation, Neoplastic);细胞质(Cytoplasm);DNA结合蛋白质类(DNA-Binding Proteins);基因缺失(Gene Deletion);基因表达(Gene Expression);绿色荧光蛋白质类(Green Fluorescent Proteins);人类(Humans);发光蛋白质类(Luminescent Proteins);淋巴结(Lymph Nodes);小鼠(Mice);分子序列数据(Molecular Sequence Data);诱变(Mutagenesis);核蛋白质类(Nuclear Proteins);肽碎片(Peptide Fragments);聚合酶链反应(Polymerase Chain Reaction);原癌基因蛋白质c-myc(Proto-Oncogene Proteins c-myc);RNA, 信使(RNA, Messenger);大鼠(Rats);阻遏蛋白质类(Repressor Proteins);酿酒酵母菌(Saccharomyces cerevisiae);脾(Spleen);构效关系(Structure-Activity Relationship);转录因子(Transcription Factors);转染(Transfection);锌指(Zinc Fingers)
DOI
10.1074/jbc.M207196200
PMID
12748187
发布时间
2021-02-09
- 浏览11
The Journal of biological chemistry
28799-811页
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