A serine protease inhibitor prevents endoplasmic reticulum stress-induced cleavage but not transport of the membrane-bound transcription factor ATF6.
作者:
主题词
激活转录因子6(Activating Transcription Factor 6);CCAAT增强子结合蛋白类(CCAAT-Enhancer-Binding Proteins);细胞核(Cell Nucleus);DNA结合蛋白质类(DNA-Binding Proteins);二硫苏糖醇(Dithiothreitol);内质网(Endoplasmic Reticulum);酶抑制剂(Enzyme Inhibitors);高尔基体(Golgi Apparatus);人类(Humans);前蛋白转化酶类(Proprotein Convertases);丝氨酸内肽酶类(Serine Endopeptidases);丝氨酸蛋白酶抑制剂(Serine Proteinase Inhibitors);胆固醇调节元件结合蛋白质1(Sterol Regulatory Element Binding Protein 1);胆固醇调节元件结合蛋白质2(Sterol Regulatory Element Binding Protein 2);砜类(Sulfones);毒胡萝卜内酯(Thapsigargin);转录因子(Transcription Factors)
DOI
10.1074/jbc.M300923200
PMID
12782636
发布时间
2021-02-06
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