换一批Overexpression of Toll-like receptor 4 amplifies the host response to lipopolysaccharide and provides a survival advantage in transgenic mice.
第一作者：
Franck,Bihl
第一单位：
Department of Human Genetics, McGill University, and Center for the Study of Host Resistance, Montreal General Hospital, Montréal, Québec, Canada.
作者：
医学主题词
佐剂, 免疫(Adjuvants, Immunologic);动物(Animals);细胞膜(Cell Membrane);细胞, 培养的(Cells, Cultured);交叉, 遗传(Crosses, Genetic);流式细胞术(Flow Cytometry);基因剂量(Gene Dosage);基因表达调控(Gene Expression Regulation);注射, 腹腔内(Injections, Intraperitoneal);脂多糖类(Lipopolysaccharides);淋巴细胞活化(Lymphocyte Activation);膜糖蛋白类(Membrane Glycoproteins);小鼠(Mice);小鼠, 近交C3H(Mice, Inbred C3H);小鼠, 近交C57BL(Mice, Inbred C57BL);小鼠, 转基因(Mice, Transgenic);受体, 细胞表面(Receptors, Cell Surface);逆转录聚合酶链反应(Reverse Transcriptase Polymerase Chain Reaction);沙门菌感染, 动物(Salmonella Infections, Animal);休克, 脓毒性(Shock, Septic);存活率(Survival Rate);Toll样受体4(Toll-Like Receptor 4);Toll样受体(Toll-Like Receptors);转基因(Transgenes)
DOI
10.4049/jimmunol.170.12.6141
PMID
12794144
发布时间
2025-05-29
- 浏览24
相似文献
- 中文期刊
- 外文期刊
- 学位论文
- 会议论文
