Toll-like receptor (TLR) 2 and TLR5, but not TLR4, are required for Helicobacter pylori-induced NF-kappa B activation and chemokine expression by epithelial cells.
第一作者:
Michael F,Smith
第一单位:
University of Virginia Health System, Digestive Health Center of Excellence and Department of Microbiology, Charlottesville, Virginia 22908-0708, USA. mfs3k@virginia.edu
作者:
医学主题词
细胞系(Cell Line);炎症趋化因子类(Chemokines);DNA, 互补(DNA, Complementary);酶激活(Enzyme Activation);上皮细胞(Epithelial Cells);鞭毛蛋白(Flagellin);基因, 显性(Genes, Dominant);基因, 报告(Genes, Reporter);幽门螺杆菌(Helicobacter pylori);人类(Humans);脂多糖类(Lipopolysaccharides);膜糖蛋白类(Membrane Glycoproteins);NF-κB(NF-kappa B);质粒(Plasmids);蛋白质结合(Protein Binding);RNA, 信使(RNA, Messenger);受体, 细胞表面(Receptors, Cell Surface);逆转录聚合酶链反应(Reverse Transcriptase Polymerase Chain Reaction);信号传导(Signal Transduction);胃(Stomach);时间因素(Time Factors);Toll样受体2(Toll-Like Receptor 2);Toll样受体4(Toll-Like Receptor 4);Toll样受体5(Toll-Like Receptor 5);Toll样受体(Toll-Like Receptors);转染(Transfection)
DOI
10.1074/jbc.M305536200
PMID
12807870
发布时间
2022-03-09
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