TNF-alpha -308A promoter polymorphism is associated with enhanced TNF-alpha production and inflammatory activity in Crohn's patients with fistulizing disease.
作者:
主题词
急相蛋白质类(Acute-Phase Proteins);青少年(Adolescent);成年人(Adult);老年人(Aged);病例对照研究(Case-Control Studies);Crohn病(Crohn Disease);皮瘘(Cutaneous Fistula);酶联免疫吸附测定(Enzyme-Linked Immunosorbent Assay);女(雌)性(Female);疾病遗传易感性(Genetic Predisposition to Disease);基因型(Genotype);人类(Humans);Logistic模型(Logistic Models);男(雄)性(Male);中年人(Middle Aged);多态现象, 遗传(Polymorphism, Genetic);启动区, 遗传(Promoter Regions, Genetic);直肠瘘(Rectal Fistula);肿瘤坏死因子α(Tumor Necrosis Factor-alpha)
DOI
10.1111/j.1572-0241.2003.07416.x
PMID
12809834
发布时间
2022-04-08
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