换一批
换一批Attenuation of the activity of the cAMP-specific phosphodiesterase PDE4A5 by interaction with the immunophilin XAP2.
作者：
主题词
1-甲基-3-异丁基黄嘌呤(1-Methyl-3-isobutylxanthine);3',5'-环AMP磷酸二酯酶类(3',5'-Cyclic-AMP Phosphodiesterases);丙氨酸(Alanine);氨基酸序列(Amino Acid Sequence);动物(Animals);COS细胞(COS Cells);克隆, 分子(Cloning, Molecular);环AMP(Cyclic AMP);环核苷酸磷酸二酯酶类, 4型(Cyclic Nucleotide Phosphodiesterases, Type 4);DNA, 互补(DNA, Complementary);剂量效应关系, 药物(Dose-Response Relationship, Drug);电泳, 聚丙烯酰氨凝胶(Electrophoresis, Polyacrylamide Gel);基因缺失(Gene Deletion);谷胱甘肽转移酶(Glutathione Transferase);人类(Humans);免疫印迹法(Immunoblotting);半数抑制浓度(Inhibitory Concentration 50);细胞内信号肽和蛋白质类(Intracellular Signaling Peptides and Proteins);分子序列数据(Molecular Sequence Data);突变(Mutation);开放读码框架(Open Reading Frames);磷酰化(Phosphorylation);沉淀素试验(Precipitin Tests);蛋白质结合(Protein Binding);蛋白质亚型(Protein Isoforms);蛋白质结构, 三级(Protein Structure, Tertiary);蛋白质类(Proteins);大鼠(Rats);重组融合蛋白质类(Recombinant Fusion Proteins);咯利普兰(Rolipram);酿酒酵母菌(Saccharomyces cerevisiae);序列同源性, 氨基酸(Sequence Homology, Amino Acid);时间因素(Time Factors);双杂交系统技术(Two-Hybrid System Techniques)
DOI
10.1074/jbc.M303269200
PMID
12810716
发布时间
2021-02-06
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