换一批
换一批Rac1 function is required for Src-induced transformation. Evidence of a role for Tiam1 and Vav2 in Rac activation by Src.
作者：
主题词
3T3细胞(3T3 Cells);等位基因(Alleles);动物(Animals);结合部位(Binding Sites);催化作用(Catalysis);细胞系(Cell Line);细胞转化, 肿瘤(Cell Transformation, Neoplastic);DNA(DNA);酶激活(Enzyme Activation);酶抑制剂(Enzyme Inhibitors);GTP磷酸水解酶类(GTP Phosphohydrolases);基因, 报告(Genes, Reporter);鸟嘌呤核苷酸交换因子类(Guanine Nucleotide Exchange Factors);人类(Humans);吲哚类(Indoles);JNK丝裂原活化蛋白激酶类(JNK Mitogen-Activated Protein Kinases);MAP激酶激酶4(MAP Kinase Kinase 4);小鼠(Mice);显微镜检查, 荧光(Microscopy, Fluorescence);丝裂原激活蛋白激酶激酶类(Mitogen-Activated Protein Kinase Kinases);丝裂原激活蛋白激酶类(Mitogen-Activated Protein Kinases);突变(Mutation);癌基因蛋白质类(Oncogene Proteins);磷酰化(Phosphorylation);质粒(Plasmids);启动区, 遗传(Promoter Regions, Genetic);蛋白质类(Proteins);原癌基因蛋白质c-jun(Proto-Oncogene Proteins c-jun);原癌基因蛋白质c-vav(Proto-Oncogene Proteins c-vav);原癌基因蛋白质类pp60(c-src)(Proto-Oncogene Proteins pp60(c-src));磺胺类(Sulfonamides);时间因素(Time Factors);转染(Transfection);酪氨酸(Tyrosine);钒酸盐类(Vanadates);rac1 GTP结合蛋白质(rac1 GTP-Binding Protein)
DOI
10.1074/jbc.M302960200
PMID
12810717
发布时间
2021-12-03
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