换一批AIP1 mediates TNF-alpha-induced ASK1 activation by facilitating dissociation of ASK1 from its inhibitor 14-3-3.
第一作者：
Rong,Zhang
第一单位：
Center for Cardiovascular Research, University of Rochester Medical Center, Rochester, New York 14642, USA.
作者：
医学主题词
14-3-3蛋白质类(14-3-3 Proteins);氨基酸序列(Amino Acid Sequence);动物(Animals);细胞凋亡(Apoptosis);碱基序列(Base Sequence);牛(Cattle);细胞, 培养的(Cells, Cultured);DNA, 互补(DNA, Complementary);内皮, 血管(Endothelium, Vascular);酶激活(Enzyme Activation);酶抑制剂(Enzyme Inhibitors);人类(Humans);MAP激酶激酶激酶5(MAP Kinase Kinase Kinase 5);MAP激酶激酶激酶类(MAP Kinase Kinase Kinases);MAP激酶信号系统(MAP Kinase Signaling System);分子序列数据(Molecular Sequence Data);重组蛋白质类(Recombinant Proteins);肿瘤坏死因子α(Tumor Necrosis Factor-alpha);双杂交系统技术(Two-Hybrid System Techniques);酪氨酸单氧化酶(Tyrosine 3-Monooxygenase);ras GTP酶激活蛋白质类(ras GTPase-Activating Proteins)
DOI
10.1172/JCI17790
PMID
12813029
发布时间
2022-03-30
基金项目
R01 HL065978/HL/NHLBI NIH HHS/United States
1R01 HL-65978-01/HL/NHLBI NIH HHS/United States
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