Essential role of IRF-3 in lipopolysaccharide-induced interferon-beta gene expression and endotoxin shock.
作者:
主题词
动物(Animals);放线菌酮(Cycloheximide);细胞因子类(Cytokines);DNA结合蛋白质类(DNA-Binding Proteins);树突细胞(Dendritic Cells);剂量效应关系, 药物(Dose-Response Relationship, Drug);内毒素类(Endotoxins);基因表达调控(Gene Expression Regulation);基因, 显性(Genes, Dominant);干扰素调节因子3(Interferon Regulatory Factor-3);干扰素调节因子7(Interferon Regulatory Factor-7);干扰素β(Interferon-beta);脂多糖类(Lipopolysaccharides);萤光素酶类(Luciferases);小鼠(Mice);蛋白质合成抑制药(Protein Synthesis Inhibitors);RNA, 信使(RNA, Messenger);逆转录聚合酶链反应(Reverse Transcriptase Polymerase Chain Reaction);信号传导(Signal Transduction);时间因素(Time Factors);转录因子(Transcription Factors);转录激活(Transcriptional Activation);增量调节(Up-Regulation)
DOI
10.1016/s0006-291x(03)01049-0
PMID
12821121
发布时间
2019-06-12
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