换一批
换一批Dual protein farnesyltransferase-geranylgeranyltransferase-I inhibitors as potential cancer chemotherapeutic agents.
作者：
主题词
烷基和芳基转移酶类(Alkyl and Aryl Transferases);动物(Animals);抗肿瘤药(Antineoplastic Agents);载体蛋白质类(Carrier Proteins);结晶学, X线(Crystallography, X-Ray);药物筛选试验, 抗肿瘤(Drug Screening Assays, Antitumor);HSP40热休克蛋白质类(HSP40 Heat-Shock Proteins);热休克蛋白质类(Heat-Shock Proteins);人类(Humans);小鼠(Mice);小鼠, 裸(Mice, Nude);模型, 分子(Models, Molecular);肿瘤移植(Neoplasm Transplantation);肿瘤, 实验性(Neoplasms, Experimental);蛋白质异戊烯化(Protein Prenylation);构效关系(Structure-Activity Relationship);移植, 异种(Transplantation, Heterologous);肿瘤细胞, 培养的(Tumor Cells, Cultured);rap1 GTP结合蛋白质类(rap1 GTP-Binding Proteins);ras蛋白质类(ras Proteins)
DOI
10.1021/jm020587n
PMID
12825937
发布时间
2007-11-15
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