换一批
换一批CHIC2 deletion, a surrogate for FIP1L1-PDGFRA fusion, occurs in systemic mastocytosis associated with eosinophilia and predicts response to imatinib mesylate therapy.
作者：
主题词
成年人(Adult);老年人(Aged);老年人, 80以上(Aged, 80 and over);苯甲酰胺类(Benzamides);嗜酸粒细胞增多(Eosinophilia);基因重排(Gene Rearrangement);造血干细胞(Hematopoietic Stem Cells);人类(Humans);嗜酸细胞增多综合征(Hypereosinophilic Syndrome);原位杂交, 荧光(In Situ Hybridization, Fluorescence);肥大细胞增生症, 系统性(Mastocytosis, Systemic);中年人(Middle Aged);癌基因蛋白质类, 融合(Oncogene Proteins, Fusion);哌嗪类(Piperazines);试验预期值(Predictive Value of Tests);前瞻性研究(Prospective Studies);嘧啶类(Pyrimidines);受体, 血小板源生长因子α(Receptor, Platelet-Derived Growth Factor alpha);逆转录聚合酶链反应(Reverse Transcriptase Polymerase Chain Reaction);序列缺失(Sequence Deletion);治疗结果(Treatment Outcome);mRNA剪切和多聚腺苷酸化因子类(mRNA Cleavage and Polyadenylation Factors)
DOI
10.1182/blood-2003-05-1627
PMID
12842979
发布时间
2021-02-06
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Blood
3093-6页
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