换一批Polymorphic variants of insulin-like growth factor I (IGF-I) receptor and phosphoinositide 3-kinase genes affect IGF-I plasma levels and human longevity: cues for an evolutionarily conserved mechanism of life span control.
第一作者：
Massimiliano,Bonafè
第一单位：
Department of Experimental Pathology, University of Bologna, 40126 Bologna, Italy. giuseppe.paolisso@unina2.it
作者：
医学主题词
青少年(Adolescent);成年人(Adult);老年人(Aged);老年人, 80以上(Aged, 80 and over);衰老(Aging);DNA结合蛋白质类(DNA-Binding Proteins);进化, 分子(Evolution, Molecular);女(雌)性(Female);叉头转录因子类(Forkhead Transcription Factors);基因频率(Gene Frequency);基因型(Genotype);人类(Humans);胰岛素(Insulin);胰岛素样生长因子Ⅰ(Insulin-Like Growth Factor I);长寿(Longevity);男(雄)性(Male);中年人(Middle Aged);磷酸肌醇3-激酶类(Phosphatidylinositol 3-Kinases);多态现象, 遗传(Polymorphism, Genetic);受体, IGF1型(Receptor, IGF Type 1);转录因子(Transcription Factors)
DOI
10.1210/jc.2002-021810
PMID
12843179
发布时间
2016-11-24
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