Pancreatic NOD beta cells express MHC class II protein and the frequency of I-A(g7) mRNA-expressing beta cells strongly increases during progression to autoimmune diabetes.
第一作者:
U,Walter
第一单位:
Department of Cellbiology and Immunology, German Research Centre for Biotechnology, Braunschweig, Germany. Ulrich.Walter@med.uni-duesseldorf.de
作者:
医学主题词
动物(Animals);CD4阳性T淋巴细胞(CD4-Positive T-Lymphocytes);糖尿病, 1型(Diabetes Mellitus, Type 1);疾病恶化(Disease Progression);基因表达调控(Gene Expression Regulation);组织相容性抗原Ⅱ类(Histocompatibility Antigens Class II);胰岛(Islets of Langerhans);小鼠(Mice);小鼠, 近交NOD(Mice, Inbred NOD);小鼠, SCID(Mice, SCID);RNA, 信使(RNA, Messenger);时间因素(Time Factors);转录, 遗传(Transcription, Genetic)
DOI
10.1007/s00125-003-1164-y
PMID
12856083
发布时间
2018-11-13
- 浏览9
Diabetologia
1106-14页
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