Inhibitors of DNA methylation and histone deacetylation activate cytomegalovirus promoter-controlled reporter gene expression in human glioblastoma cell line U87.
第一作者:
G,Grassi
第一单位:
Department of Molecular Pathology, University Hospital of Tübingen, Liebermeisterstrasse 8, D-72076, Tübingen, Germany. ggrassi@units.it
作者:
医学主题词
动物(Animals);阿扎胞苷(Azacitidine);巨细胞病毒(Cytomegalovirus);DNA甲基化(DNA Methylation);DNA复制(DNA Replication);流式细胞术(Flow Cytometry);基因表达调控, 肿瘤(Gene Expression Regulation, Neoplastic);基因沉默(Gene Silencing);胶质母细胞瘤(Glioblastoma);组蛋白脱乙酰基酶类(Histone Deacetylases);组蛋白类(Histones);人类(Humans);羟肟酸类(Hydroxamic Acids);显微镜检查, 荧光(Microscopy, Fluorescence);模型, 理论(Models, Theoretical);质粒(Plasmids);聚合酶链反应(Polymerase Chain Reaction);启动区, 遗传(Promoter Regions, Genetic);蛋白质合成抑制药(Protein Synthesis Inhibitors);时间因素(Time Factors);转染(Transfection);肿瘤细胞, 培养的(Tumor Cells, Cultured)
DOI
10.1093/carcin/bgg118
PMID
12869421
发布时间
2013-11-21
- 浏览132
Carcinogenesis
1625-35页
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