Drug interaction of spirapril hydrochloride monohydrate and hydrochlorothiazide. A clinical study to compare the pharmacokinetics after administration of spirapril hydrochloride monohydrate tablets, hydrochlorothiazide tablets and fixed combination bi-layer tablets.
第一作者:
Michael,Schürer
第一单位:
LAFAA Laboratory for Contract Research in Clinical Pharmacology and Biopharmaceutical Analytics GmbH, Bad Schwartau, Germany. lafaa_gmbh@t-online.de
作者:
医学主题词
成年人(Adult);血管紧张素转换酶抑制药(Angiotensin-Converting Enzyme Inhibitors);曲线下面积(Area Under Curve);生物利用度(Biological Availability);利尿药(Diuretics);复方合剂(Drug Combinations);药物相互作用(Drug Interactions);依那普利(Enalapril);半衰期(Half-Life);人类(Humans);氢氯噻嗪(Hydrochlorothiazide);男(雄)性(Male);单盲法(Single-Blind Method);钠氯同向转运体抑制剂(Sodium Chloride Symporter Inhibitors);片剂(Tablets)
DOI
10.1055/s-0031-1297129
PMID
12872612
发布时间
2013-11-21
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Arzneimittel-Forschung
414-9页
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