A promoter region of the midkine gene that is frequently expressed in human hepatocellular carcinoma can activate a suicide gene as effectively as the alpha-fetoprotein promoter.
作者:
主题词
老年人(Aged);抗病毒药(Antiviral Agents);癌, 肝细胞(Carcinoma, Hepatocellular);载体蛋白质类(Carrier Proteins);病例对照研究(Case-Control Studies);细胞因子类(Cytokines);女(雌)性(Female);更昔洛韦(Ganciclovir);基因表达调控, 肿瘤(Gene Expression Regulation, Neoplastic);人类(Humans);肝(Liver);肝肿瘤(Liver Neoplasms);萤光素酶类(Luciferases);男(雄)性(Male);中年人(Middle Aged);启动区, 遗传(Promoter Regions, Genetic);调控序列, 核酸(Regulatory Sequences, Nucleic Acid);单纯疱疹病毒属(Simplexvirus);胸苷激酶(Thymidine Kinase);转录激活(Transcriptional Activation);肿瘤细胞, 培养的(Tumor Cells, Cultured);甲胎蛋白类(alpha-Fetoproteins)
DOI
10.1038/sj.bjc.6601246
PMID
12966430
发布时间
2018-11-30
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British journal of cancer
1086-90页
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