Generation of free radicals during the reductive metabolism of nilutamide by lung microsomes: possible role in the development of lung lesions in patients treated with this anti-androgen.
第一作者:
V,Berger
第一单位:
INSERM U24 Hôpital Beaujon, Clichy, France.
作者:
主题词
雄激素拮抗药(Androgen Antagonists);动物(Animals);自由基(Free Radicals);人类(Humans);过氧化氢(Hydrogen Peroxide);咪唑类(Imidazoles);咪唑啉啶类(Imidazolidines);肺(Lung);肺疾病(Lung Diseases);男(雄)性(Male);微粒体(Microsomes);NADP(NADP);硝基化合物(Nitro Compounds);氧化还原(Oxidation-Reduction);氧耗量(Oxygen Consumption);大鼠(Rats);大鼠, 近交系(Rats, Inbred Strains);超氧化物类(Superoxides)
DOI
10.1016/0006-2952(92)90593-8
PMID
1311586
发布时间
2019-06-23
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