Differences in the longevity of topo IIalpha and topo IIbeta drug-stabilized cleavable complexes and the relationship to drug sensitivity.
作者:
主题词
安吖啶(Amsacrine);动物(Animals);抗原, 肿瘤(Antigens, Neoplasm);抗肿瘤药(Antineoplastic Agents);抗肿瘤药, 植物(Antineoplastic Agents, Phytogenic);DNA拓扑异构酶类, Ⅱ型(DNA Topoisomerases, Type II);DNA, 肿瘤(DNA, Neoplasm);DNA结合蛋白质类(DNA-Binding Proteins);依托泊甙(Etoposide);成纤维细胞(Fibroblasts);荧光素-5-异硫氰酸盐(Fluorescein-5-isothiocyanate);荧光抗体技术(Fluorescent Antibody Technique);荧光染料(Fluorescent Dyes);半衰期(Half-Life);同工酶类(Isoenzymes);动力学(Kinetics);小鼠(Mice);米托蒽醌(Mitoxantrone)
DOI
10.1007/s00280-003-0701-1
PMID
14504921
发布时间
2022-03-11
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