换一批Selective gamma-hydroxybutyric acid receptor ligands increase extracellular glutamate in the hippocampus, but fail to activate G protein and to produce the sedative/hypnotic effect of gamma-hydroxybutyric acid.
第一作者：
M Paola,Castelli
第一单位：
Neuroscienze S.c.a r.l., Cagliari, Italy.
作者：
医学主题词
动物(Animals);放射自显影术(Autoradiography);苯并环庚烯类(Benzocycloheptenes);结合, 竞争性(Binding, Competitive);脑化学(Brain Chemistry);细胞外间隙(Extracellular Space);GABA拮抗剂(GABA Antagonists);GTP结合蛋白质类(GTP-Binding Proteins);谷氨酸(Glutamic Acid);鸟苷5'-O-(3-硫代三磷酸)(Guanosine 5'-O-(3-Thiotriphosphate));海马(Hippocampus);羟丁酸盐类(Hydroxybutyrates);催眠药和镇静药(Hypnotics and Sedatives);配体(Ligands);男(雄)性(Male);小鼠(Mice);小鼠, 近交DBA(Mice, Inbred DBA);微透析(Microdialysis);有机磷化合物(Organophosphorus Compounds);大鼠(Rats);大鼠, Sprague-Dawley(Rats, Sprague-Dawley);受体, 细胞表面(Receptors, Cell Surface);反射(Reflex)
DOI
10.1046/j.1471-4159.2003.02037.x
PMID
14535954
发布时间
2019-06-30
- 浏览16
Journal of neurochemistry
722-32页
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