换一批Induction of an antitumor immunological response by an intratumoral injection of dendritic cells pulsed with genetically engineered Semliki Forest virus to produce interleukin-18 combined with the systemic administration of interleukin-12.
第一作者：
Ryuya,Yamanaka
第一单位：
Clinical Gene Therapy Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland, USA. ryaman@pop11.odn.ne.jp
作者：
医学主题词
动物(Animals);抗体生成(Antibody Formation);抗原, CD(Antigens, CD);脑肿瘤(Brain Neoplasms);仓鼠亚科(Cricetinae);DNA引物(DNA Primers);DNA, 互补(DNA, Complementary);树突细胞(Dendritic Cells);遗传工程(Genetic Engineering);神经胶质瘤(Glioma);免疫遗传学(Immunogenetics);免疫疗法, 主动(Immunotherapy, Active);白细胞介素12(Interleukin-12);白细胞介素18(Interleukin-18);杀伤细胞, 天然(Killer Cells, Natural);男(雄)性(Male);小鼠(Mice);小鼠, 近交C57BL(Mice, Inbred C57BL);逆转录聚合酶链反应(Reverse Transcriptase Polymerase Chain Reaction);西门利克森林病毒(Semliki forest virus);T淋巴细胞, 辅助诱导(T-Lymphocytes, Helper-Inducer);转导, 遗传(Transduction, Genetic);肿瘤细胞, 培养的(Tumor Cells, Cultured)
DOI
10.3171/jns.2003.99.4.0746
PMID
14567611
发布时间
2012-11-15
- 浏览84
Journal of neurosurgery
746-53页
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