换一批
换一批Progress report of a Phase I study of the intracerebral microinfusion of a recombinant chimeric protein composed of transforming growth factor (TGF)-alpha and a mutated form of the Pseudomonas exotoxin termed PE-38 (TP-38) for the treatment of malignant brain tumors.
作者：
主题词
成年人(Adult);老年人(Aged);脑肿瘤(Brain Neoplasms);药物评价, 临床前(Drug Evaluation, Preclinical);外毒素类(Exotoxins);女(雌)性(Female);胶质母细胞瘤(Glioblastoma);人类(Humans);输注, 胃肠外(Infusions, Parenteral);男(雄)性(Male);最大耐受剂量(Maximum Tolerated Dose);中年人(Middle Aged);铜绿假单胞菌(Pseudomonas aeruginosa);重组融合蛋白质类(Recombinant Fusion Proteins);存活率(Survival Rate);转化生长因子α(Transforming Growth Factor alpha);治疗结果(Treatment Outcome)
DOI
10.1023/a:1026290315809
PMID
14649883
发布时间
2019-09-11
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