SAR development of polycyclic guanine derivatives targeted to the discovery of a selective PDE5 inhibitor for treatment of erectile dysfunction.
作者:
主题词
3',5'-环GMP磷酸二酯酶类(3',5'-Cyclic-GMP Phosphodiesterases);环核苷酸磷酸二酯酶类, 5型(Cyclic Nucleotide Phosphodiesterases, Type 5);药物释放系统(Drug Delivery Systems);勃起功能障碍(Erectile Dysfunction);鸟嘌呤(Guanine);人类(Humans);男(雄)性(Male);磷酸二酯酶抑制剂(Phosphodiesterase Inhibitors);多环化合物(Polycyclic Compounds);构效关系(Structure-Activity Relationship)
DOI
10.1016/j.bmcl.2003.12.027
PMID
14980684
发布时间
2013-11-21
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