Conditional inactivation of the MEN1 gene leads to pancreatic and pituitary tumorigenesis but does not affect normal development of these tissues.
作者:
主题词
动物(Animals);胚胎, 哺乳动物(Embryo, Mammalian);外显子(Exons);女(雌)性(Female);基因沉默(Gene Silencing);增生(Hyperplasia);胰岛素瘤(Insulinoma);整合酶类(Integrases);男(雄)性(Male);小鼠(Mice);小鼠, 近交C57BL(Mice, Inbred C57BL);小鼠, 基因敲除(Mice, Knockout);多发性内分泌瘤病1型(Multiple Endocrine Neoplasia Type 1);胰腺(Pancreas);胰腺肿瘤(Pancreatic Neoplasms);垂体(Pituitary Gland);垂体肿瘤(Pituitary Neoplasms);催乳素瘤(Prolactinoma);转基因(Transgenes);病毒蛋白质类(Viral Proteins)
DOI
10.1128/MCB.24.8.3125-3131.2004
PMID
15060136
发布时间
2021-05-26
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Molecular and cellular biology
3125-31页
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