Alpha-T-catenin is expressed in human brain and interacts with the Wnt signaling pathway but is not responsible for linkage to chromosome 10 in Alzheimer's disease.
第一作者:
Victoria,Busby
第一单位:
Department of Neuroscience, Institute of Psychiatry, De Crespigny Park, London SE5 8AF, United Kingdom.
作者:
医学主题词
老年人(Aged);老年人, 80以上(Aged, 80 and over);选择性剪接(Alternative Splicing);阿尔茨海默病(Alzheimer Disease);淀粉样β肽类(Amyloid beta-Peptides);动物(Animals);脑(Brain);脑化学(Brain Chemistry);病例对照研究(Case-Control Studies);细胞系(Cell Line);染色体图(Chromosome Mapping);染色体, 人, 10对(Chromosomes, Human, Pair 10);细胞支架蛋白质类(Cytoskeletal Proteins);DNA突变分析(DNA Mutational Analysis);女(雌)性(Female);基因表达(Gene Expression);基因频率(Gene Frequency);基因连锁(Genetic Linkage);基因检测(Genetic Testing);基因型(Genotype);人类(Humans);男(雄)性(Male);小鼠(Mice);多态现象, 遗传(Polymorphism, Genetic);原癌基因蛋白质类(Proto-Oncogene Proteins);信号传导(Signal Transduction);Wnt蛋白质类(Wnt Proteins);α连环素(alpha Catenin)
DOI
10.1385/NMM:5:2:133
PMID
15075440
发布时间
2018-11-13
- 浏览3
Neuromolecular medicine
133-46页
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