LIGHT sensitizes IFN-gamma-mediated apoptosis of HT-29 human carcinoma cells through both death receptor and mitochondria pathways.
第一作者:
Man Chao,Zhang
第一单位:
Division of Hematology/Oncology, Department of Internal Medicine, the University of Michigan, Ann Arbor, MI 48109-0934, USA. manchaoz@umich.edu
作者:
医学主题词
氨基酸氯甲基酮类(Amino Acid Chloromethyl Ketones);细胞凋亡(Apoptosis);半胱氨酸天冬氨酸蛋白酶(Caspases);半胱氨酸蛋白酶抑制剂(Cysteine Proteinase Inhibitors);酶激活(Enzyme Activation);HT29细胞(HT29 Cells);人类(Humans);干扰素γ(Interferon-gamma);膜蛋白质类(Membrane Proteins);线粒体(Mitochondria);寡肽类(Oligopeptides);原癌基因蛋白质c-bcl-2(Proto-Oncogene Proteins c-bcl-2);受体, 肿瘤坏死因子(Receptors, Tumor Necrosis Factor);信号传导(Signal Transduction);肿瘤坏死因子配体超家族成员14(Tumor Necrosis Factor Ligand Superfamily Member 14);肿瘤坏死因子α(Tumor Necrosis Factor-alpha);bcl-2同源拮抗杀伤蛋白质(bcl-2 Homologous Antagonist-Killer Protein);bcl-X蛋白质(bcl-X Protein)
DOI
10.1038/sj.cr.7290210
PMID
15115612
发布时间
2012-11-15
- 浏览18
Cell research
117-24页
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