The isoflavonoids genistein and quercetin activate different stress signaling pathways as shown by analysis of site-specific phosphorylation of ATM, p53 and histone H2AX.
第一作者:
Ruiqiong,Ye
第一单位:
Department of Biochemistry & Molecular Biology, University of Calgary, 3330 Hospital Drive, N.W., Calgary, Alta., Canada T2N 4N1.
作者:
主题词
细胞周期蛋白质类(Cell Cycle Proteins);DNA损伤(DNA Damage);DNA结合蛋白质类(DNA-Binding Proteins);酶激活(Enzyme Activation);染料木黄酮(Genistein);组蛋白类(Histones);人类(Humans);异黄酮类(Isoflavones);磷酰化(Phosphorylation);沉淀素试验(Precipitin Tests);槲皮素(Quercetin);信号传导(Signal Transduction);肿瘤细胞, 培养的(Tumor Cells, Cultured);肿瘤抑制蛋白质p53(Tumor Suppressor Protein p53);肿瘤抑制蛋白质类(Tumor Suppressor Proteins)
DOI
10.1016/j.dnarep.2003.10.014
PMID
15177039
发布时间
2021-12-03
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DNA repair
235-44页
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