Identification of the structural requirements for mutagenicity by incorporating molecular flexibility and metabolic activation of chemicals I: TA100 model.
第一作者:
Ovanes,Mekenyan
第一单位:
Laboratory of Mathematical Chemistry, University Prof. As. Zlatarov, 8010 Bourgas, Bulgaria, Human & Environmental Safety, The Procter & Gamble Company, MVL, Cincinnati, Ohio 45239-8707, USA. omekenya@btu.bg
作者:
医学主题词
生物转化(Biotransformation);计算机模拟(Computer Simulation);决策树(Decision Trees);诱变(Mutagenesis);诱变力试验(Mutagenicity Tests);诱变剂(Mutagens);量化构效关系(Quantitative Structure-Activity Relationship);鼠伤寒沙门菌(Salmonella typhimurium)
DOI
10.1021/tx030049t
PMID
15206896
发布时间
2004-06-21
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