Differentiating the functional role of hypoxia-inducible factor (HIF)-1alpha and HIF-2alpha (EPAS-1) by the use of RNA interference: erythropoietin is a HIF-2alpha target gene in Hep3B and Kelly cells.
第一作者:
Christina,Warnecke
第一单位:
Department of Nephrology and Medical Intensive Care, Virchow Clinic, Charité University Medicine, Berlin, Germany. christina.warnecke@med4.imed.uni-erlangen.de
作者:
主题词
碱性螺旋-环-螺旋转录因子类(Basic Helix-Loop-Helix Transcription Factors);细胞系(Cell Line);细胞系, 肿瘤(Cell Line, Tumor);增强子元件, 遗传学(Enhancer Elements, Genetic);红细胞生成素(Erythropoietin);基因, 报告(Genes, Reporter);人类(Humans);缺氧诱导因子1, α亚基(Hypoxia-Inducible Factor 1, alpha Subunit);蛋白质亚单位(Protein Subunits);RNA干扰(RNA Interference);RNA, 信使(RNA, Messenger);RNA, 小分子干扰(RNA, Small Interfering);反应元件(Response Elements);敏感性与特异性(Sensitivity and Specificity);反式激活因子类(Trans-Activators);转录因子(Transcription Factors);转录激活(Transcriptional Activation);转染(Transfection)
DOI
10.1096/fj.04-1640fje
PMID
15240563
发布时间
2018-11-30
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FASEB journal
1462-4页
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