Variability in the benzodiazepine response of serotonin 5-HT1A receptor null mice displaying anxiety-like phenotype: evidence for genetic modifiers in the 5-HT-mediated regulation of GABA(A) receptors.
作者:
主题词
杏仁核(Amygdala);动物(Animals);抗焦虑药(Anti-Anxiety Agents);焦虑症(Anxiety Disorders);交叉, 遗传(Crosses, Genetic);地西泮(Diazepam);抗药性(Drug Resistance);上位性, 遗传(Epistasis, Genetic);额叶(Frontal Lobe);基因表达调控(Gene Expression Regulation);基因表达调控, 发育期(Gene Expression Regulation, Developmental);迷宫学习(Maze Learning);小鼠(Mice);小鼠, 近交C57BL(Mice, Inbred C57BL);蛋白质相互作用图谱(Protein Interaction Mapping);蛋白质亚单位(Protein Subunits);RNA, 信使(RNA, Messenger);受体, 血清素, 5-HT1A(Receptor, Serotonin, 5-HT1A);受体, GABA-A(Receptors, GABA-A)
DOI
10.1523/JNEUROSCI.0563-04.2004
PMID
15254090
发布时间
2020-02-25
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The Journal of neuroscience
6343-51页
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