Antitumor activity of ZD6126, a novel vascular-targeting agent, is enhanced when combined with ZD1839, an epidermal growth factor receptor tyrosine kinase inhibitor, and potentiates the effects of radiation in a human non-small cell lung cancer xenograft model.
作者:
主题词
动物(Animals);抗肿瘤药(Antineoplastic Agents);抗肿瘤联合化疗方案(Antineoplastic Combined Chemotherapy Protocols);癌, 非小细胞肺(Carcinoma, Non-Small-Cell Lung);细胞系, 肿瘤(Cell Line, Tumor);内皮, 血管(Endothelium, Vascular);酶抑制剂(Enzyme Inhibitors);表皮生长因子(Epidermal Growth Factor);女(雌)性(Female);免疫组织化学(Immunohistochemistry);Ki-67抗原(Ki-67 Antigen);肺肿瘤(Lung Neoplasms);小鼠(Mice);小鼠, 近交BALB C(Mice, Inbred BALB C);小鼠, 裸(Mice, Nude);坏死(Necrosis);肿瘤移植(Neoplasm Transplantation);新生血管化, 病理性(Neovascularization, Pathologic);有机磷化合物(Organophosphorus Compounds);蛋白激酶抑制剂(Protein Kinase Inhibitors);喹唑啉类(Quinazolines);信号传导(Signal Transduction);时间因素(Time Factors)
PMID
15299080
发布时间
2020-09-30
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