换一批The presenilin C-terminus is required for ER-retention, nicastrin-binding and gamma-secretase activity.
第一作者：
Christoph,Kaether
第一单位：
Laboratory for Alzheimer's and Parkinson's Disease Research, Department of Biochemistry, Adolf-Butenandt-Institute, Ludwig-Maximilians-Universität, München, Germany. ckaether@med.uni-muenchen.de
作者：
医学主题词
氨基酸序列(Amino Acid Sequence);淀粉样前体蛋白分泌酶类(Amyloid Precursor Protein Secretases);动物(Animals);COS细胞(COS Cells);内肽酶类(Endopeptidases);内质网(Endoplasmic Reticulum);膜糖蛋白类(Membrane Glycoproteins);膜蛋白质类(Membrane Proteins);分子序列数据(Molecular Sequence Data);早老素1(Presenilin-1);蛋白质结合(Protein Binding);蛋白分选信号(Protein Sorting Signals);蛋白质结构, 三级(Protein Structure, Tertiary);重组融合蛋白质类(Recombinant Fusion Proteins);序列比对(Sequence Alignment)
DOI
10.1038/sj.emboj.7600478
PMID
15549135
发布时间
2019-12-10
- 浏览3
The EMBO journal
4738-48页
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