The use of liquid chromatography-atmospheric pressure chemical ionization mass spectrometry to explore the in vitro metabolism of cyanoalkyl piperidine derivatives.

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第一作者： E,Kantharaj

第一单位： In Vitro Pharmacokinetics, Department of ADME/Tox, Johnson & Johnson Pharmaceutical Research and Development, Turnhiutseweg 30, B-2340, Beerse, Belgium. kethiraj@prdbe.jnj.com

作者： E,Kantharaj ^[1] ; Peter B,Ehmer ; Katie,De Wagter ; An,Tuytelaars ; Pascale E A,Proost ; Claire,Mackie ; Ron A H J,Gilissen

作者单位： In Vitro Pharmacokinetics, Department of ADME/Tox, Johnson & Johnson Pharmaceutical Research and Development, Turnhiutseweg 30, B-2340, Beerse, Belgium. kethiraj@prdbe.jnj.com ^[1]

主题词色谱法, 液相(Chromatography, Liquid);人类(Humans);微粒体, 肝(Microsomes, Liver);腈类(Nitriles);哌啶类(Piperidines);光谱法, 质量, 电喷雾电离(Spectrometry, Mass, Electrospray Ionization)

DOI 10.1002/bmc.449

PMID 15627277

发布时间 2005-04-07

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准确一般字义偏差语意偏离译文作用小提交