Disruption of the BCL11B gene through inv(14)(q11.2q32.31) results in the expression of BCL11B-TRDC fusion transcripts and is associated with the absence of wild-type BCL11B transcripts in T-ALL.
第一作者:
G K,Przybylski
第一单位:
Institute of Human Genetics, Polish Academy of Sciences, Poznan, Poland. przybylg@man.poznan.pl
作者:
医学主题词
碱基序列(Base Sequence);染色体图(Chromosome Mapping);染色体, 人, 11对(Chromosomes, Human, Pair 11);染色体, 人, 14对(Chromosomes, Human, Pair 14);DNA结合蛋白质类(DNA-Binding Proteins);基因缺失(Gene Deletion);人类(Humans);白血病淋巴瘤, 成人T细胞(Leukemia-Lymphoma, Adult T-Cell);分子序列数据(Molecular Sequence Data);阻遏蛋白质类(Repressor Proteins);转录, 遗传(Transcription, Genetic);易位, 遗传(Translocation, Genetic);肿瘤抑制蛋白质类(Tumor Suppressor Proteins)
DOI
10.1038/sj.leu.2403619
PMID
15668700
发布时间
2013-03-04
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Leukemia
201-8页
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