Opioids inhibit purinergic nociceptors in the sensory neurons and fibres of rat via a G protein-dependent mechanism.
第一作者:
I,Chizhmakov
第一单位:
Department of Cellular Membranology, Bogomoletz Institute of Physiology, Kiev, Ukraine.
作者:
医学主题词
动作电位(Action Potentials);腺苷三磷酸(Adenosine Triphosphate);动物(Animals);动物, 新生(Animals, Newborn);细胞, 培养的(Cells, Cultured);药物相互作用(Drug Interactions);GTP结合蛋白质类(GTP-Binding Proteins);神经节, 脊(Ganglia, Spinal);鸟苷5'-O-(3-硫代三磷酸)(Guanosine 5'-O-(3-Thiotriphosphate));鸟苷二磷酸(Guanosine Diphosphate);男(雄)性(Male);膜电位(Membrane Potentials);纳洛酮(Naloxone);麻醉品拮抗药(Narcotic Antagonists);麻醉品(Narcotics);神经传导(Neural Conduction);神经元, 传入(Neurons, Afferent);膜片钳术(Patch-Clamp Techniques);百白咳毒素(Pertussis Toxin);氯化钾(Potassium Chloride);大鼠(Rats);大鼠, Wistar(Rats, Wistar);受体, 嘌呤能P2(Receptors, Purinergic P2);受体, 嘌呤能P2X(Receptors, Purinergic P2X);皮肤(Skin)
DOI
10.1016/j.neuropharm.2004.12.009
PMID
15814099
发布时间
2014-11-20
- 浏览14
Neuropharmacology
639-47页
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