Hepatocyte growth factor is a preferred in vitro substrate for human hepsin, a membrane-anchored serine protease implicated in prostate and ovarian cancers.
第一作者:
Sylvia,Herter
第一单位:
Department of Biology, Amgen San Francisco, 1120 Veterans Boulevard, South San Francisco, CA 94080, USA.
作者:
医学主题词
结合部位(Binding Sites);细胞系, 肿瘤(Cell Line, Tumor);酶激活(Enzyme Activation);女(雌)性(Female);基因表达(Gene Expression);肝细胞生长因子(Hepatocyte Growth Factor);人类(Humans);男(雄)性(Male);卵巢肿瘤(Ovarian Neoplasms);前列腺肿瘤(Prostatic Neoplasms);蛋白质构象(Protein Conformation);丝氨酸内肽酶类(Serine Endopeptidases);底物特异性(Substrate Specificity);增量调节(Up-Regulation)
DOI
10.1042/BJ20041955
PMID
15839837
发布时间
2018-11-13
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