tBid induces alterations of mitochondrial fatty acid oxidation flux by malonyl-CoA-independent inhibition of carnitine palmitoyltransferase-1.
作者:
主题词
与BH3相互作用的凋亡激活蛋白质(BH3 Interacting Domain Death Agonist Protein);心磷脂质类(Cardiolipins);肉碱O-软脂酰转移酶(Carnitine O-Palmitoyltransferase);载体蛋白质类(Carrier Proteins);半胱氨酸天冬氨酸蛋白酶(Caspases);细胞膜通透性(Cell Membrane Permeability);细胞, 培养的(Cells, Cultured);细胞色素c类(Cytochromes c);脂肪酸类(Fatty Acids);肝细胞(Hepatocytes);人类(Humans);丙二酰辅酶A(Malonyl Coenzyme A);膜电位(Membrane Potentials);膜蛋白质类(Membrane Proteins);线粒体, 肝(Mitochondria, Liver);氧化还原(Oxidation-Reduction);蛋白质结合(Protein Binding);原癌基因蛋白质c-bcl-2(Proto-Oncogene Proteins c-bcl-2);bcl-2同源拮抗杀伤蛋白质(bcl-2 Homologous Antagonist-Killer Protein)
DOI
10.1038/sj.cdd.4401636
PMID
15846373
发布时间
2012-11-15
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