换一批
换一批A novel targeted therapy of Leydig and granulosa cell tumors through the luteinizing hormone receptor using a hecate-chorionic gonadotropin beta conjugate in transgenic mice.
作者：
主题词
氨基酸氯甲基酮类(Amino Acid Chloromethyl Ketones);动物(Animals);细胞凋亡(Apoptosis);印迹法, RNA(Blotting, Northern);半胱氨酸天冬氨酸蛋白酶3(Caspase 3);半胱氨酸天冬氨酸蛋白酶(Caspases);细胞死亡(Cell Death);细胞系, 肿瘤(Cell Line, Tumor);细胞分离(Cell Separation);绒毛膜促性腺激素, β亚单位, 人(Chorionic Gonadotropin, beta Subunit, Human);疾病模型, 动物(Disease Models, Animal);酶激活(Enzyme Activation);女(雌)性(Female);流式细胞术(Flow Cytometry);粒层细胞瘤(Granulosa Cell Tumor);人类(Humans);莱迪希细胞瘤(Leydig Cell Tumor);男(雄)性(Male);蜂毒肽(Melitten);小鼠(Mice);小鼠, 近交C57BL(Mice, Inbred C57BL);小鼠, 转基因(Mice, Transgenic);显微镜检查, 荧光(Microscopy, Fluorescence);坏死(Necrosis);卵巢肿瘤(Ovarian Neoplasms);孕酮(Progesterone);启动区, 遗传(Promoter Regions, Genetic);蛋白质结构, 三级(Protein Structure, Tertiary);受体, LH(Receptors, LH);重组融合蛋白质类(Recombinant Fusion Proteins);睾丸肿瘤(Testicular Neoplasms);时间因素(Time Factors)
DOI
10.1593/neo.04751
PMID
15967102
发布时间
2019-06-08
- 浏览16
Neoplasia (New York, N.Y.)
497-508页
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