换一批Multiple elements jointly determine inhibitor selectivity of cyclic nucleotide phosphodiesterases 4 and 7.
第一作者：
Huanchen,Wang
第一单位：
Department of Biochemistry and Biophysics and Lineberger Comprehensive Cancer Center, The University of North Carolina, Chapel Hill, North Carolina 27599-7260, USA.
作者：
医学主题词
1-甲基-3-异丁基黄嘌呤(1-Methyl-3-isobutylxanthine);3',5'-环AMP磷酸二酯酶类(3',5'-Cyclic-AMP Phosphodiesterases);氨基酸序列(Amino Acid Sequence);结晶学, X线(Crystallography, X-Ray);环AMP(Cyclic AMP);环核苷酸磷酸二酯酶类, 4型(Cyclic Nucleotide Phosphodiesterases, Type 4);环核苷酸磷酸二酯酶类, 7型(Cyclic Nucleotide Phosphodiesterases, Type 7);人类(Humans);模型, 分子(Models, Molecular);分子序列数据(Molecular Sequence Data);分子结构(Molecular Structure);磷酸二酯酶抑制剂(Phosphodiesterase Inhibitors);蛋白质结构, 三级(Protein Structure, Tertiary);序列比对(Sequence Alignment)
DOI
10.1074/jbc.M504398200
PMID
15994308
发布时间
2021-02-09
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