Repression of c-kit and its downstream substrates by GATA-1 inhibits cell proliferation during erythroid maturation.
第一作者:
Veerendra,Munugalavadla
第一单位:
Herman B. Wells Center for Pediatric Research, Indiana University School of Medicine, Cancer Research Institute, 1044 W. Walnut Street, Room 425, Indianapolis, IN 46202, USA. vmunugal@iupui.edu
作者:
主题词
动物(Animals);细胞凋亡(Apoptosis);细胞分化(Cell Differentiation);细胞系, 转化(Cell Line, Transformed);细胞增殖(Cell Proliferation);克隆细胞(Clone Cells);DNA结合蛋白质类(DNA-Binding Proteins);红系细胞(Erythroid Cells);红系细胞特异性DNA结合因子类(Erythroid-Specific DNA-Binding Factors);红细胞生成素(Erythropoietin);GATA1转录因子(GATA1 Transcription Factor);基因表达调控(Gene Expression Regulation);生长抑制物(Growth Inhibitors);小鼠(Mice);原癌基因蛋白质类c-kit(Proto-Oncogene Proteins c-kit);阻遏蛋白质类(Repressor Proteins);信号传导(Signal Transduction);干细胞因子(Stem Cell Factor);底物特异性(Substrate Specificity);转录因子(Transcription Factors);src族激酶类(src-Family Kinases)
DOI
10.1128/MCB.25.15.6747-6759.2005
PMID
16024808
发布时间
2020-07-21
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