Polymorphisms in the insulin receptor substrate-1 (IRS-1) gene and the insulin receptor substrate-2 (IRS-2) gene influence glucose homeostasis and body mass index in women with polycystic ovary syndrome and non-hyperandrogenic controls.
作者:
主题词
成年人(Adult);氨基酸取代(Amino Acid Substitution);人体质量指数(Body Mass Index);女(雌)性(Female);基因频率(Gene Frequency);葡萄糖(Glucose);内环境稳定(Homeostasis);人类(Humans);雄激素增多症(Hyperandrogenism);胰岛素受体底物蛋白质类(Insulin Receptor Substrate Proteins);胰岛素抗药性(Insulin Resistance);细胞内信号肽和蛋白质类(Intracellular Signaling Peptides and Proteins);肥胖症(Obesity);磷蛋白类(Phosphoproteins);多囊卵巢综合征(Polycystic Ovary Syndrome);多态现象, 遗传(Polymorphism, Genetic);受体, 胰岛素(Receptor, Insulin);西班牙(Spain)
DOI
10.1093/humrep/dei205
PMID
16037106
发布时间
2022-12-07
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